Talindrew

Molecular biology MCP server: 90 tools for plasmid maps, restriction digests and gels, PCR primer design and Tm, CRISPR guides, OpenCloning-compatible cloning, PubMed and a lab notebook. Remote, OAuth, free tier.

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Dokumentation

Talindrew MCP server: molecular biology tools for Claude, ChatGPT, Codex and Cursor

Talindrew is a browser-based molecular biology platform (plasmid editor, cloning design, primer design, lab notebook, protein structure prediction and drug discovery). Its remote MCP server gives any MCP client 90 molecular biology tools that run on Talindrew's engines, so numbers like a primer's Tm or a digest's fragment sizes are computed, not recalled from a model's memory.

https://mcp.talindrew.com/mcp
  • Transport: Streamable HTTP
  • Sign-in: OAuth with your Google account (the first sign-in creates a free Talindrew account)
  • Server name: talindrew
  • Website and per-client guides: https://www.talindrew.com/mcp

This repository holds the connection details and setup instructions only. The server is hosted by Talindrew; there is nothing to install or run locally.

Connect

Claude (claude.ai, desktop and mobile)

  1. Open Customize → Connectors (claude.ai/customize/connectors), click + Add → Add custom connector.
  2. Paste https://mcp.talindrew.com/mcp, click Connect, sign in with Google and click Allow.
  3. In a chat, ask for something Talindrew does and approve the tool when Claude asks.

Team and Enterprise: an owner adds it under Organization settings → Connectors; members then click Connect. Guide: https://www.talindrew.com/mcp/claude

Claude Code

claude mcp add --transport http --scope user talindrew https://mcp.talindrew.com/mcp

Then run /mcp, choose talindrew and Authenticate. Guide: https://www.talindrew.com/mcp/claude-code

ChatGPT

  1. Open chatgpt.com/plugins, click + and choose Add custom MCP server.
  2. Name it Talindrew, paste https://mcp.talindrew.com/mcp as the server URL and choose OAuth.
  3. Create it as a plugin and sign in with Google when asked. In a chat, type @ and pick Talindrew.

Guide: https://www.talindrew.com/mcp/chatgpt

Codex

codex mcp add talindrew --url https://mcp.talindrew.com/mcp
codex mcp login talindrew

Guide: https://www.talindrew.com/mcp/codex

Cursor, VS Code, Windsurf, Zed, Cline and other JSON-configured clients

{
  "mcpServers": {
    "talindrew": { "type": "http", "url": "https://mcp.talindrew.com/mcp" }
  }
}

Step-by-step pages for 23 clients, including Gemini CLI, Goose, opencode, Continue, Kiro, Warp, LM Studio, Raycast, Perplexity, Mistral and Microsoft Copilot Studio: https://www.talindrew.com/mcp

What you can ask

  • "Fetch pUC19 from Addgene, cut it with EcoRI and PvuII and show me the gel."
  • "Design primers to clone GFP into pET-28a by Gibson assembly, and check them for hairpins."
  • "Find SpCas9 guides in the first exon of human TP53 and rank them."
  • "Codon-optimise this protein for E. coli and give me the CAI."
  • "Find recent PubMed papers on base editing in iPSCs and summarise the abstracts."
  • "Write today's cloning into my lab notebook with the map and the primer table."

Tools

GroupToolsPlan
Sequence analysisanalyze_sequence, find_restriction_sites (600+ enzymes, Dam/Dcm), digest_sequence, detect_features, find_orfs, translate_dna, align_sequences, simulate_gelFree
Primers, CRISPR and proteinsdesign_primers, primer_tm (nearest-neighbour, Wallace, salt-adjusted), mutagenesis_primers, find_crispr_guides, protein_properties, optimize_codons, reverse_translate, ligation_calculatorFree
Cloning workspace (OpenCloning-compatible)create_workspace, import_sequence, import_from_repository (Addgene, Benchling, SnapGene, iGEM, Euroscarf, NCBI), add_cloning_step (restriction, ligation, Gibson, Golden Gate, Gateway, PCR, recombination, CRISPR), design_cloning_primers, check_primers, check_sequencing, domesticate_part, export_workspace and moreFree
Literature and databasessearch_pubmed, get_pubmed_abstracts, search_europepmc, search_genes (NCBI Gene), search_addgeneFree
Your Talindrew accountsequences, workspaces, lab-notebook entries, exports (PDF, Word, Markdown) and sharingFree
Structure prediction and drug discoveryrun_model (Boltz-2, AlphaFold 2, ESMFold, DiffDock and more), start_foldrx_run (fold → pockets → screen → dock → rank)Pro / Max

The full, current list is on https://www.talindrew.com/mcp.

Pricing

Connecting is free. The Free plan includes 25 tool calls a week (reset every Monday, 00:00 UTC). Plus ($9/month or $99/year, 7-day free trial) makes tool calls unlimited. Structure prediction and drug-discovery runs need Pro or Max. Details: https://www.talindrew.com/pricing

Privacy and access

Each client gets its own OAuth token scoped to your account, and you can revoke it any time in Talindrew under Settings → Connected apps. Read-only scopes cannot write. Nothing in your account is shared unless you share it. Privacy policy: https://www.talindrew.com/privacy

Links