Alliance of Genome Resources (JS)

A high-performance JavaScript server for the Alliance of Genome Resources (AGR) MCP.

AGR MCP Server

MCP server for querying Alliance of Genome Resources - genomics data across model organisms.

Installation

Option 1: npx (Recommended)

No installation required. Add to your MCP client config:

{
  "mcpServers": {
    "agr-genomics": {
      "command": "npx",
      "args": ["-y", "agr-mcp-server"]
    }
  }
}

Option 2: Global install

npm install -g agr-mcp-server

Then use in your config:

{
  "mcpServers": {
    "agr-genomics": {
      "command": "agr-mcp-server"
    }
  }
}

Config file locations

ClientConfig path
Claude Desktop (macOS)~/Library/Application Support/Claude/claude_desktop_config.json
Claude Desktop (Windows)%APPDATA%\Claude\claude_desktop_config.json
Claude Code~/.claude/settings.json
CursorSettings > MCP Servers
Windsurf~/.codeium/windsurf/mcp_config.json

Usage

Ask questions naturally:

  • "Search for BRCA1 genes in human"
  • "What genes are involved in DNA repair?"
  • "Get information about HGNC:1100"
  • "Find orthologs of insulin gene"
  • "What diseases are associated with TP53?"
  • "Show me expression data for daf-2 in worm"

Supported Species

Human, mouse, rat, zebrafish, fly, worm, yeast, xenopus

Tools

ToolDescription
search_genesSearch genes with optional species filter
get_gene_infoDetailed gene information (symbol, location, synonyms)
get_gene_diseasesDisease associations for a gene
search_diseasesSearch diseases by name
get_gene_expressionExpression data across tissues/stages
find_orthologsCross-species homologs
get_gene_phenotypesPhenotype annotations
get_gene_interactionsMolecular and genetic interactions
get_gene_allelesAlleles/variants for a gene
search_allelesSearch alleles by name
get_species_listList supported model organisms

Gene ID Formats

SpeciesFormatExample
HumanHGNC:*HGNC:1100
MouseMGI:*MGI:95892
RatRGD:*RGD:3889
ZebrafishZFIN:ZDB-GENE-*ZFIN:ZDB-GENE-990415-72
FlyFB:FBgn*FB:FBgn0000017
WormWB:WBGene*WB:WBGene00000898
YeastSGD:S*SGD:S000002536
XenopusXenbase:XB-GENE-*Xenbase:XB-GENE-485905

Data Sources

License

MIT

Related Servers